Clinical Theatre 1

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Manchester primary and secondary care teams worked collaboratively within the system to develop quality improvement methodologies to improve opioid stewardship system wide. The outcomes of the interventions resulted in an overall reduction in opioid prescribing and a harmonised approach to reducing the harm from opioids.

The NCEPOD Treat as One A National Confidential Enquiry into Patient Outcome and Deaths (NCEPOD) Report highlighted: • Only 72% of patients had their mental health drugs prescribed during the initial assessment. • Discharge notification lacked the mental health medication in 29% of patients. • Clozapine, most commonly used in treatment resistant schizophrenia, is considered a critical medicine. Clozapine requires careful initiation, must be re-titrated if doses omitted for more than 48 hours and has several serious adverse effects which must be monitored. Mental Health In-Reach has been operating for two years ‘Bridging the gap between mental and physical healthcare in general hospitals’ with a mental health pharmacist supporting the acute hospital pharmacy team. This has improved acute staff confidence is managing clozapine and enabled effective interventions to improve patient care.

Introduction to AI in Pharmacy: • Definition and relevance to pharmacy. • Current trends and future potential. Benefits of AI in Pharmacy: • Enhanced accuracy and efficiency in dispensing and inventory. • Improved efficiency and therefore capacity • Personalised medicine through predictive analytics. Challenges and Barriers: • Concerns about AI replacing human roles. • Ensuring data privacy and ethical use. Examples of Successful AI Applications: • Automated dispensing systems. • AI-powered document processing. How to Approach AI Implementation: • Selecting and evaluating AI tools. • Integrating AI into workflows. • Continuous evaluation and updates. Ethical and Legal Considerations: • Maintaining data privacy and transparency. • Complying with legal and ethical standards. Conclusion: • Recap of key takeaways. • Future directions and staying ahead

A talk on migraines; covering epidemiology, pathophysiology, diagnosis, and lifestyle and pharmaceutical management. Includes information and advice about the latest anti-CGRP and Gepant therapies.

How to prescribe, adjust and manage medicines in patients with liver disease, considering pharmacokinetic and pharmacodynamic factors and adverse drug reactions etc., as well as considering the type of liver disease. We will also discuss particular classes of drugs which often raise concerns in liver disease.